By Topic

Development of a large-scale computer heart model for supporting clinical studies of arrhythmias

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

6 Author(s)
Sugimachi, M. ; Dept. of Cardiovascular Dynamics, Nat. Cardiovascular Center Research Inst., Suita, Japan ; Inagaki, M. ; Nakazawa, K. ; Suzuki, T.
more authors

Although a large number of studies on cardiac electrical properties have been conducted, it remains difficult to integrate all fragmented data into one unified framework. As an approach to this, we developed a large-scale (6 × 106 elements) three-dimensional simulator of cardiac electrical activity based on human ventricular geometry and experimentally derived ionic channel models. This simulator has the advantages over previous simulators in that ventricular fibrillation can be induced with clinical programmed extrastimulation, fibrillation can be induced more easily by extrastimulation at right ventricular outflow tract as in a clinical situation, and it is possible to examine the contribution of early afterdepolarization to arrhythmogenecity in patients with e.g., long QT syndrome. These advantages indicate that our simulator is useful in supporting a wide range of clinical studies of arrhythmias.

Published in:

Engineering in Medicine and Biology Society, 2001. Proceedings of the 23rd Annual International Conference of the IEEE  (Volume:1 )

Date of Conference: