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Multicode CDMA with V-BLAST architecture is an attractive scheme to achieve high data rate transmission. We propose an advanced detection scheme, order partial parallel interference cancellation with decision feedback (DF-OPPIC), to combat co-antenna interference and multiple access interference in the system. Compared with the original reference, the scheme has better performance on the frame error ratio in flat Rayleigh fading channel and multipath Rayleigh fading channel. Moreover, due to the avoidance of calculating pseudo-inverse and optimal detection order in every time of iteration, the scheme has lower arithmetic complexity.