By Topic

A silicon lab-on-chip for integrated sample preparation by PCR and DNA analysis by hybridization

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

12 Author(s)
Fuchs, A. ; Lab. Biopuces, Grenoble, France ; Jeanson, H. ; Claustre, P. ; Gruss, J.A.
more authors

LabOnChip devices are emerging around the world as new tools to characterize biological events and samples. They offer new solutions for fast, specific, automated, low cost and high throughput analysis. By merging proprietary technologies of the French Atomic Energy Commission (CEA-Grenoble, France) and ST Microelectronics, we have developed prototypes of a disposable stand-alone point-of-care device which performs DNA sample preparation and analysis on grafted DNA probes. The presented prototypes consist of a 3 cm2 silicon core presenting integrated microfluidics using embedded channels, DNA bearing electrodes, heat resistors and temperature control. Results presented demonstrate the technological and biological compatibilities of the device and give preliminary results of PCR and hybridization efficiencies

Published in:

Microtechnologies in Medicine & Biology 2nd Annual International IEEE-EMB Special Topic Conference on

Date of Conference:

2002