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This paper describes the column oriented butted regular architecture-algorithmic behavioral synthesis (COBRA-ABS) high-level synthesis tool which has been designed to synthesize DSP algorithms, specified in C, onto multi-field programmable gate array (FPGA) custom computing machines (FCCMs). COBRA-ABS performs synthesis using a new simulated annealing-based methodology, which maps the specified behavior into a four-dimensional (4-D) space and then optimizes the implied architecture. COBRA-ABS synthesizes custom very long instruction word (VLIW) style architectures partitioned across the FPGAs of the FCCM and has been used to compile C algorithms down to FPGA configuration bit-streams. This paper describes the tool and synthesis concepts and presents simulation results from a number of synthesized fast Fourier transform (FFT) related algorithms.