Referenced Items are not available for this document.
The human immunodeficiency virus (HIV) infection, that causes acquired immune deficiency syndrome (AIDS), is a dynamic process that can be modeled via differential equations. The primary goal of this paper is to introduce a control philosophy to boost the response of the immune system by means of drug scheduling. The control purpose is to steer the system to an equilibrium condition known as long-term nonprogressor, which corresponds to an infected patient that does not develop the symptoms of AIDS. The feasibility of the control methodology is illustrated via simulations on two HIV dynamic models and on a general disease model.
Published in:
Automation Science and Engineering, IEEE Transactions on
(Volume:6
,
Issue:
2
)
Date of Publication: April 2009
- Page(s):
- 248 - 255
- ISSN :
- 1545-5955
- INSPEC Accession Number:
- 10547380
- Digital Object Identifier :
- 10.1109/TASE.2008.2008156
- Date of Publication :
- 27 January 2009
- Date of Current Version :
- 31 March 2009
- Issue Date :
- April 2009
- Sponsored by :
- IEEE Robotics and Automation Society
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