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Computer visualization of long genomic sequences

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5 Author(s)
Wu, D. ; Illinois Inst. of Technol., Chicago, IL, USA ; Roberge, J. ; Cork, D.J. ; Nguyen, B.G.
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Human beings find it difficult to analyze local and global oligonucleotide patterns in the linear primary sequences of a genome. In this paper, we present a family of iterated function systems (IFS) that can be used to generate a set of visual models of a DNA sequence. A new visualization function, the W-curve, that is derived from this IFS family is introduced. Using W-curves, a user can readily compare subsequences within a long genomic sequence - or between genomic sequences - and can visually evaluate the effect of local variations (mutations) upon the global genomic information content

Published in:

Visualization, 1993. Visualization '93, Proceedings., IEEE Conference on

Date of Conference:

25-29 Oct 1993