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A differential viscosity detector for use in miniaturized chemical separation systems

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7 Author(s)
Blom, M.T. ; MESA Res. Inst., Univ. of Twente, Enschede, Netherlands ; Chmela, E. ; van der Heyden, F.H.J. ; Oosterbroek, R.E.
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We present a micromachined differential viscosity detector suitable for integration into an on-chip hydrodynamic chromatography system. The general design, however, is applicable to any liquid chromatography system that is used for separation of polymers. The micromachined part of the detector consists of a fluidic Wheatstone bridge and a low hydraulic capacitance pressure sensor of which the pressure sensing is based on optical detection of a membrane deflection. The stand-alone sensor shows a resolution in specific viscosity of 3×10-3, in which specific viscosity is defined as the increase in viscosity by a sample, relative to the baseline viscosity of a solvent.

Published in:

Microelectromechanical Systems, Journal of  (Volume:14 ,  Issue: 1 )

Date of Publication:

Feb. 2005

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