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Sensor networks, a new class of devices has the potential to revolutionize the capture, processing, and communication of critical data for use by first responders. CodeBlue integrates sensor nodes and other wireless devices into a disaster response setting and provides facilities for ad hoc network formation, resource naming and discovery, security, and in-network aggregation of sensor-produced data. We designed CodeBlue for rapidly changing, critical care environments. To test it, we developed two wireless vital sign monitors and a PDA-based triage application for first responders. Additionally, we developed MoteTrack, a robust radio frequency (RF)-based localization system, which lets rescuers determine their location within a building and track patients. Although much of our work on CodeBlue is preliminary, our initial experience with medical care sensor networks raised many exciting opportunities and challenges.