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This paper reports a biosystem (biological system) for analyzing biochemical substances in biological fluids. Rather than one channel, it comprises 16 highly-selective optical-channels that enable the measurement of the concentration of 16 different biochemical substances. An array of 16-optical filters with high reflectivity and low absorption loss has been designed using dielectric films. Each filter is sensitive in a single wavelength with a FWHM (Full-Width-Half-Maximum) <5 nm and peak intensity >52%. A commercially available band-pass optical filter with a band-pass wavelength in 450-600 nm is used to enable the use of a white light source for biosystem illumination. Preliminary tests with a single-channel are successfully demonstrated.