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An array of platinum electrodes has been integrated with analog and digital circuitry in standard CMOS technology for stimulation and recording of natural neural networks. The array utilizes a shifted electrode design that has been electrically characterized and modeled. The electrode and its circuitry form a repeatable unit, which can be multiplied to achieve a larger array. Each circuitry unit contains a buffer for stimulation and a bandpass filter for readout. In contrast to traditional electrode arrays used for measuring action potentials, this device is capable of on-chip signal filtering, improving the signal to noise ratio (SNR), on-chip analog to digital conversation (preventing further signal degradation), and simultaneous recording and stimulation.