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High spatial resolution, focused electrical stimulation of electrically-excitable tissue

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3 Author(s)
Laflen, J.B. ; Dept. of Biomed. Eng., Purdue Univ., West Lafayette, IN, USA ; Talavage, T.M. ; Sarychev, A.K.

A theoretical method is presented which uses wave-guiding principles to construct a focused point of stimulation at any location within a region of electrically-excitable tissue. The excitation is formed through the constructive interference of different frequency wave energies, traveling at frequency-dependent velocities, which coalesce at the stimulation point. Further energy is brought to the stimulation point through reflection(s) at the boundaries of the wave-guiding structure. The resulting excitation signal depends upon several factors, including pulse envelope and duration, allowable frequency range, and stimulation time. A necessary trade-off exists amongst stimulation time, pulse duration, and the degree of focus.

Published in:

Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint  (Volume:3 )

Date of Conference:

23-26 Oct. 2002

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