SPR sensor for detection of /spl beta/2-microglobulin

An optical fiber sensor based on the resonant coupling between a surface plasmon wave and a guided mode of the optical fiber sensor has been reported. A technique based on the surface plasmon resonance phenomenon offers a sensitive method for studying the stability of optical sensors. In this work, the authors consider a layered structure consisting of three-layer optical waveguides incorporating silver-monolayer of bovine serum albumin coating layers. Tests include exposing these films to /spl beta/2-microglobulin have been studied. Experimental and theoretical results have been mutually compared, and the operation characteristics of this novel sensing device have been briefly described.