Near-infrared fluorescent nanoprobes for non-invasive multimodal tissue imaging

Near-infrared (NIR) fluorescence imaging has become an important modality for the non-invasive imaging of living tissues because of its low absorption and scattering. Although NIR fluorescence imaging has the capability of non-invasive deep tissue imaging with a low auto-fluorescence, its spatial resolution is not enough to show a three-dimensional object's location with an anatomical resolution. To overcome this problem, we have developed NIR fluorescent multimodal nanoprobes for non-invasive tissue imaging.