A fused pH and fluorescence sensor using the same sensing area

A fused pH and fluorescence sensor is proposed, and a prototype has been fabricated using CMOS silicon integrated circuit technology. Fluorescence intensity and pH can be detected at the same pixel for the first time. In the proposed device, a pH sensor which uses CCD image sensor technology and a filter-less fluorescence detection sensor are fused in the same pixel, enabling fluorescence and pH signals to be detected simultaneously in the same sensing area.