A distinguished panel of experts from global industry and academia will debate the nature of systems that will drive the killer applications of 2020. Can we really forecast these future killer applications? We have had the computing revolution, then communications, and now, the sensor revolution. Are sensors driving the future killer applications? Are there any other revolutions in sight? What circuits and system innovations can ISSCC bring forward to enable the next killer applications? What unique technology elements, device structures and memory architectures will be required? Should we continue with silicon technology and seek breakthroughs in system architecture, algorithms, SoC integration and packaging? Or, are we preparing for “beyond silicon” technologies? And if so, which beyond-silicon technologies are realisitic for the future, versus forever being technologies of the future?