A high-sensitivity human muscle-vibration measurement (MMG) sensor adapted to clinical use is presented. The muscle vibration phenomenon is modeled and investigated to optimize the measurement technique. The sensor uses an acoustic impedance adaptation technique to convert the skin surface vibration in terms of acoustic pressure, which is sensed by a microphone. The device is calibrated and gives the real amplitude of the vibration. It is also well fitted to measure other physiological vibrations in the 2 Hz-1 kHz range.