A method for analyzing the urbanization process from multitemporal SPOT 5 panchromatic images is presented. The analysis is performed by unsupervised change detection between built-up presence indicators extracted separately from the scenes. The obtained index has an effective resolution which is coarser than the Ground Sample Distance, thus allowing a good spatial match between the indicators. Then, a local Mixed Information change indicator is employed in order to capture the non-linear temporal behaviors. A region-based approach is developed in synergy with the local Mixed Information in order to process consistently large scenes which may be affected by regional acquisition distortions. Experiments are conducted on SPOT 5 scenes acquired in 2003 and 2008 which cover a suburban area (45×45 km2) of the city of Tangshan in China. The urbanization detector is validated by visual interpretation, giving an equal omission/commission probability of 10%. A comparison to linear change indicators highlights an improvement of 15% of the equal omission/commission probability.