Increasing expansion of power systems and grids are accompanied nowadays by innovation in smart grid solutions to maintain systems stability. This paper proposes an intelligent wide area synchrophasor based system (IWAS) for predicting and mitigating transient instabilities. The IWAS incorporates artificial neural networks (ANN) for transient stability prediction. The ANN makes use of the advent of phasor measurements units (PMU) for real-time prediction. Coherent groups of generators-which swing together-is identified through an algorithm based on PMU measurements. A remedial action scheme (RAS) is applied to counteract the system instability by splitting the system into islands and initiate under frequency load shedding actions. The potential of the proposed approach is tested using New England 39 bus system.