We have evaluated the perpendicular giant magnetoimpedance effect (GMI) in both NiFe and NiFe/Cu/NiFe films with meander geometry in the >1 MHz high-frequency range. With the magnetic field, the perpendicular GMI effect shows an intense GMI peak value at a certain field. This effect is comparable to the longitudinal GMI effect in both profile and peak value amplitude. The experimental results correspond well with the predictions of a single-domain rotational magnetization model. These findings demonstrate that the deflection of the anisotropy to a perpendicular direction plays an important role in the perpendicular GMI effect.