The response of the human eye to flicker depends on the type of lamp used. Standard flickermeters measure the voltage across the lamp and assumes a 60-W incandescent lamp as a light source. When a different lamp is the light flicker source, standard flickermeters give erroneous results. This paper presents a dynamic model of the eye-brain response to flicker. The model is based on the analysis of the light emitted by the lamp. A suitable measurement system has been developed, and three different kinds of lamps have been considered. Experimental results show how the emitted light spectra and the human eye response to different colors combined to determine the level of annoyance. The uncertainty affecting such results, which arises from the hardware of the developed system, has been also estimated.