A new robust neuro-fuzzy controller for autonomous and intelligent robot manipulators in dynamic and partially known environments containing moving obstacles is presented. The navigation is based on a fuzzy technique for the idea of artificial potential fields (APFs) using analytic harmonic functions. Unlike the fuzzy technique, the development of APFs is computationally intensive. A computationally efficient processing scheme for fuzzy navigation to reasoning about obstacle avoidance using APF is described, namely, the intelligent dynamic motion planning. An integration of a robust controller and a modified Elman neural networks (MENNs) approximation-based computed-torque controller is proposed to deal with unmodeled bounded disturbances and/or unstructured unmodeled dynamics of the robot arm. The MENN weights are tuned online, with no off-line learning phase required. The stability of the overall closed-loop system, composed by the nonlinear robot dynamics and the robust neuro-fuzzy controller, is guaranteed by the Lyapunov theory. The purpose of the robust neuro-fuzzy controller is to generate the commands for the servo-systems of the robot so it may choose its way to its goal autonomously, while reacting in real-time to unexpected events. The proposed scheme has been successfully tested. The controller also demonstrates remarkable performance in adaptation to changes in manipulator dynamics. Sensor-based motion control is an essential feature for dealing with model uncertainties and unexpected obstacles in real-time world systems.