Previous research has focused on developing a brain-controlled switch named the low frequency asynchronous switch design (LF-ASD) that is suitable for intermittent control of devices such as environmental control systems, computers, and neural prostheses. On-line implementations of the LF-ASD have shown promising results in response to actual index finger flexions with able-bodied subjects. This paper reports the results of initial on-line evaluations of the LF-ASD brain-controlled switch with both able-bodied subjects and subjects with high-level spinal-cord injuries. This paper has demonstrated that users can activate the LF-ASD switch by imagining movement. In this paper, two able-bodied subjects were able to control the LF-ASD with imagined voluntary movements with hit (true positive) rates above 70% and false positive rates below 3% while two subjects with high-level spinal-cord injuries demonstrated hit rates ranging from 45-48% and false positive rates below 1%.