In this research, a distributed simulation system to easily evaluate a very large manufacturing system by synchronizing several different simulators is developed. We designed the distributed simulation system using the High Level Architecture (HLA) as the IEEE1516 standard. A manufacturing adapter to connect manufacturing system simulators with HLA using a plug-in style is proposed. The developed distributed simulation system is confirmed using a case to evaluate a hypothetical manufacturing system which produces motors. Three major commercial based manufacturing system simulators, QUEST, SIMPLE++, and GAROPS, are connected using the developed manufacturing adapter. The storage model method to connect simulation models and synchronize the simulators is used in the case study. A case study is then carried out to evaluate the performance of the cooperative work.