Nanowires have a great potential in many industrial applications, including electronics and sensors. Palladium nanowire network-based hydrogen sensors have been found to outperform their counterparts that consist of an individual nanowire or palladium thin or thick films. However, reliability issues still need to be addressed. In this paper, we consider hydrogen gas sensors based on a nanowire network with either an equilateral triangle lattice or a hexagonal lattice structure. We then provide the reliability behavior of the nanosensor under each model. Our findings reveal that one can improve the reliability function by considering a network of nanowires rather than a single nanowire. Among many other applications, our results can also be used to assess the reliability of any nanosystem/ nanodevice where one of our proposed structures is a reasonable choice. What distinguishes our work from related work are the unique difficulties that the nanocomponents introduce to the evaluation of reliability and the way that we define reliability over cycles of hydrogen gas.