It is a synthesized and complicated big production activity for advanced orbit traffic equipment manufacturing, which needs bulkiness and high content technology, so the informationization is necessary. The amalgamation phase model (between Informationization and enterprise) was given. On the base of this, informationization should be used in some case of advanced orbit traffic equipment manufacturing quality management. The original and behindhand management method can not realize the real dynamic quality management in quality management actuality. Then the quality management system design was given, which used the data mining, network system structure, dynamic quality management and B/S structure. The model function structure includes power management, collection data management etc. Meanwhile, the quality management system was developed, which has construction log management subsystems. Finally, information technology was given. The practicability, validity and economy of the system were proved through the application in some advanced orbit traffic equipment manufacturing companies.