The calculation of pitch point in the counter flow heat exchanger used in low-temperature waste heat powered Organic Rankine cycle is investigated. Detailed calculations of a HRSG with binary mixture fluids of different composition have been done on the base of pinch point analysis. The influence of binary mixture composition on the temperature distribution in the counter flow heat recovery organic steam generator (HRSG) used in low-temperature is investigated through the detailed calculations. The results show that the temperature profile as well as the locations of the pinch points is determined by the mixture compositions. Moreover, the performances of the heat exchanger are influenced by the mixture compositions. Therefore, the composition of the mixture is required to be optimized as to get a better temperature match between the two heat transfer fluids in the heat exchanger.