A configurable, record capacity extensible and nonuniformity reducible of high speed camera is designed in this paper. The CMOS image sensor lupa-300 which is produced by Cypress Corporation is used for the system. There is nonuniformity existed in the sensor. The two point method of the image with real time correction algorithm has applied to process the image nonuniformity. Then the corrected image is stored into the NandFlash array. To improve the record speed and extend record capacity, the pipelining and parallel bus mechanism is adopted. The experiment which is based on hardware platform indicates the camera can take about 250 f/s at a resolution of 640*480, the consistent storage speed is up to 614.4 Mb/s, consistent transmit from flash to camera link speed up to 1.093 Gb/s. The system record time is up to 18.6 minutes.