The main motivation in using intensity attributes to analyze and compare the technologies of mammography images acquisition is that such images are intrinsically of low contrast, which hinders the lesions detection and interpretation. Considering the viewing conditions, the study is under development to validate the influence of the contrast variation of many types of equipment on the radiologist's diagnosis. However, for the image processing, the contrast variation can be considered a problem affecting the detection of important structures. A large-intensity variation in a digitized image can be manipulated by image-processing techniques and aid in lesion detection. However, low-intensity variation, as observed in the images of full-field digital mammography systems, can impede the detection of some lesions types, as masses are structures of low contrast. Therefore, the new technologies should be tested and validated for an adequate calibration according to the procedures adjacent to the image acquisition itself.