The present paper describes an attempt to apply an approximate noninteractive control to the load-following operation of the nuclear steam supply (NSS) system of a pressurized water reactor power plant. A control strategy is proposed for maximizing the unique merit of the noninteractive control in advancing the operational performance of the NSS system. An noninteractive load follow-up control system is designed based on the idea of approximate model-following. The authors make the design method more flexible and widely applicable to more general control problems by introducing some modifications to the method proposed by Cook. Digital simulations and graphical studies based on the Bode-diagram demonstrate the effectiveness of the noniniteractive load follow-up control as well as the applicability of the proposed design method.