In this paper, optical pulse compression using a comblike profiled fiber (CPF) is theoretically and experimentally studied, in which highly nonlinear fibers and single-mode fibers are alternately concatenated. Stationary rescaled pulse (SRP), is the main focus, which is a recently discovered nonlinear stationary pulse in CPF. The fundamental characteristics of SRP are investigated, and SRP propagation is applied to the design of the CPF pulse compressor. Using the proposed design method, the specifications of the CPF can easily be controlled, such as the compression ratio per step of the CPF or the pedestal of the output pulse. Two experimental results of pulse compression using the CPF based on the proposed design method are shown: 1) pulse compression with a large compression ratio per step of the CPF and 2) low-pedestal and wideband wavelength-tunable compression. A parametric noise-amplification phenomenon occurring in a compression process for an optical pulse sequence is also numerically analyzed.