Moving from the need for a simple and versatile method for outage computation in various contexts of interest in wireless communications, in this paper we propose a lognormal approximation for the linear combination of a set of lognormal random variables (RV) with one-sided random weights. The approximation is based on a generalization of the well known moment matching approximation (MMA) for the sum of lognormal RVs, and it allows quite simple handling of the power sum of interfering signals even in rather complicated scenarios. Specifically, composite multiplicative channel models with unequal parameters can be handled, and generic (unequal) correlation patterns for some channel components can be handled with reference to any pair of signals. At this stage of the computation, only moments of the random weights are required. The probability density function of the random weight for the useful signal component may be required in computing outage probability, and numerical methods may be only required to solve a single integral at this second stage. The suitability of the approximation is examined by evaluating outage performance for various values of system parameters in some contexts of interest, namely spread spectrum systems and typical reuse-based systems with composite Rayleigh-lognormal and Nakagami-lognormal channels.