For oncological studies, the whole-body PET (WB-PET) image plays an important role in detecting and staging various cancers, but there are some potential pitfalls in traditional display methods that need to be improved. The purpose of this study is to develop several data-processing techniques to overcome these problems and provide better image quality for visual interpretation of scans. We have developed a 3-D integrated display system that fully utilizes the scan data derived from routine PET imaging protocols. This system is applicable to all PET scan data and particularly helpful for the visual interpretation of the upper torso. In our experiments, the system provided anatomical hints without the help of any other imaging modalities and was an efficient tool for the diagnosis of PET studies. Our study suggests that routine WB-PET image interpretation should consist of both emission and transmission images to optimize the perception of data and improve the accuracy of lesion localization.