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Energy window optimization in simultaneous technetium-99m TCT andthallium-201 SPECT data acquisition

Jia Li   Tsui, B.M.W.   Welch, A.   Frey, E.C.   Gullberg, G.T.  
Dept. of Biomed. Eng., North Carolina Univ., Chapel Hill, NC;

This paper appears in: Nuclear Science, IEEE Transactions on
Publication Date: Aug 1995
Volume: 42,  Issue: 4
On page(s): 1207-1213
Meeting Date: 10/30/1994 - 11/05/1994
Location: Norfolk, VA, USA
ISSN: 0018-9499
References Cited: 17
CODEN: IETNAE
INSPEC Accession Number: 5053452
Digital Object Identifier: 10.1109/23.467877
Posted online: 2002-08-06 19:12:36.0

Abstract
In simultaneous Tc-99m TCT and Tl-201 SPECT data acquisition, the emission images are degraded by not only scatter from the emission source, but also cross-contamination from the transmission photons. Also, the transmission images are degraded by scatter from the transmission source and cross-contamination from the emission photons. In this work, a criterion based on maximizing a figure-of-merit (FOM) was used to reduce image degradations by optimizing the position and width of the energy windows used in the data acquisition in a triple-camera fan-beam SPECT system. The FOM determines a compromise between increased detection efficiency of primary photons and reduction of scatter and cross-contamination photons. Scatter in the projection data was modeled using Monte Carlo (MC) simulation methods. Experimental studies were performed to verify the simulations and to estimate the amount of Pb X-rays and scatter in the collimator which were not modeled in the MC program. Results suggest that cross-contamination degrades the emission and transmission data. However, the contamination does not significantly alter the optimal energy window settings, which should be centered at ~77 keV with a window width of ~34% for detecting the Ti emission photons, and centered at 140 keV with a window width of ~20% for detecting the Tc transmission photons

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