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Distributed 3-D iterative reconstruction for quantitative SPECT

Ju, Z.-W.   Frey, E.C.   Tsui, B.M.W.  
Dept. of Biomed. Eng., North Carolina Univ., Chapel Hill, NC;

This paper appears in: Nuclear Science, IEEE Transactions on
Publication Date: Aug 1995
Volume: 42,  Issue: 4
On page(s): 1301-1309
Meeting Date: 10/30/1994 - 11/05/1994
Location: Norfolk, VA, USA
ISSN: 0018-9499
References Cited: 16
CODEN: IETNAE
INSPEC Accession Number: 5053464
Digital Object Identifier: 10.1109/23.467865
Posted online: 2002-08-06 19:12:39.0

Abstract
We describe a distributed three dimensional (3-D) iterative reconstruction library for quantitative single-photon emission computed tomography (SPECT). This library includes 3-D projector-backprojector pairs (PBPs) and distributed 3-D iterative reconstruction algorithms. The 3-D PBPs accurately and efficiently model various combinations of the image degrading factors including attenuation, detector response and scatter response. These PBPs were validated by comparing projection data computed using the projectors with that from direct Monte Carlo (MC) simulations. The distributed 3-D iterative algorithms spread the projection-backprojection operations for all the projection angles over a heterogeneous network of single or multi-processor computers to reduce the reconstruction time. Based on a master/slave paradigm, these distributed algorithms provide dynamic load balancing and fault tolerance. The distributed algorithms were verified by comparing images reconstructed using both the distributed and non-distributed algorithms. Computation times for distributed 3-D reconstructions running on up to 4 identical processors were reduced by a factor approximately 80-90% times the number of the processors participating, compared to those for non-distributed 3-D reconstructions running on a single processor. When combined with faster affordable computers, this library provides an efficient means for implementing accurate reconstruction and compensation methods to improve quality and quantitative accuracy in SPECT images

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