A review of RNA — Seq reads mapping algorithm

With the rapid development of bioinformatics, high-throughput sequencing technology is also progressing rapidly. RNA-Seq sequencing technology as an important part of genomic. At the same time, The massive data generated by RNA-Seq sequencing has made a significant contribution to the research and development of genomic. In the analysis of genomic data, the reads mapping sequence alignment process is the first step in the bioinformatics data analysis, and it is also an important part. The quality of the sequence alignment results and the speed of the run will have an impact on the next data analysis process. The objective of this paper is to discuss the RNA-Seq reads mapping algorithm and the existing sequence alignment tools, and compare and analyze the reads mapping algorithms.