Chinese medicine sugar crystallization based on soft measurement

This paper deals with the design of model-based soft measurement to improve the process monitoring and control in Chinese medicine sugar crystallization. A model dedicated to Chinese medicine sugar crystallization is designed, without consideration of crystal size distribution. The mass of crystals in the solution, the concentration of dissolved sugar and the purity are relevant to improve the manufacturing process. As these physicochemical properties are not measurable on-line, a model-based soft measurement is developed. The effectiveness of the soft measurement is demonstrated using real data from a Chinese medicine sugar crystallization process.