Characterization of the fourier spatial frequencies of time resolved laser speckle from interacting high density lipoprotein disks

Fourier spatial frequency analysis of 2-D laser speckle images was used to identify the interaction of high density lipoprotein (HDL) nanoparticles in aqueous suspension at different ionic strengths. The decorrelation function of a time series of laser speckle images was used to identify key spectral ranges of HDL samples, and characteristic frequencies were extracted. These families of frequencies can be used as unique identifiers of nanometer scale structure in particle suspensions.