Biomedical effect the phenomenon of in vivo blood oxyhemoglobin photodissociation

The results in vivo investigation the phenomenon of laser-induced photodissociation of blood oxyhemoglobin and its biomedical applications are presented. New method of control in individual response to the effect of laser radiation is proposed. Novel optical method of determination the therapeutic “dose” based on the response of changes in tissue oxygen concentration in dependence on wavelength and intensity of laser radiation has been developed. It is shown that in order to make the methods of phototherapy as well as laser therapy really efficient one has to control the oxygen concentration in tissue keeping it at the necessary level.