A 90nm CMOS transimpedance amplifier design for nanopore based DNA nucleotide sequencer

A three stage transimpedance amplifier design for nanopore based DNA nucleotide sequencing, using the 90nm IBM CMOS process is reported. It uses a cascade of a differential folded cascode and a common source stage to deliver high gain. The design demonstrates a DC gain (low frequency gain) of 60 dB along with an unity gain frequency of 200MHz. The circuit's performance has been simulated using a 1.2 V power supply. The paper provides details of the DC, AC, transient and noise analysis of this transimpedance amplifier design.