Neural recording system with low-noise analog front-end and comparator-based cyclic ADC

This paper describes a low-noise neural recording integrated circuit composed of a low-noise analog front-end (AFE) and a low-power analog-to-digital converter (ADC). The AFE amplifies biopotentials and the ADC converts input signal to digital output. The AFE exhibits 53.4dB of mid-band gain, 38.8Hz–10.6kHz of −3dB bandwidth. Total input referred noise (IRN) of AFE is 10.8μVrms and noise efficiency factor (NEF) is 8.1. The ADC achieves 10bit resolution and operates at 2.5MS/s. The chip is fabricated and successfully tested in a 0.18μm CMOS process.