Enhancement of color retinal images in poor imaging conditions

One of the first accounts of retinal observation in vivo was perhaps Jean Mery's now famous report to the French Royal Academy of Sciences in 1684. The French anatomist described how immersing a cat underwater allowed him to observe the retina in more details [1]. Nowadays a large range of retinal imaging instruments exists (e.g. flood imaging, optical scanning laser ophthalmoscopy, optical coherence tomography, etc. [2]) together with sophisticated techniques to correct for the eye's optical aberrations (e.g. adaptive optics, deconvolution [3]).