Single Photon Avalanche Diode in standard CMOS 0.5um technology

In this paper, we proposed a SPAD design that can be implemented in very low cost standard CMOS 0.5um technology. And we showed our preliminary test results of a microfluidic channel design. By integrating the microfluidic channel on top of the SPAD chip, we will get a portable molecular diagnostic system. Currently, most molecular diagnostic systems use non reusable consumables for sample processing. Because our design will use microbeads as the bio-molecule carrier, and we can easily deliver and wash away the micro-beads through the microfluidic channel, eventually, we can design a reusable and portable molecular diagnostic platform.