A bidirectional 64-channel neurochip for recording and stimulation neural network activity

We present the design and measurements of a novel 64 channel ASIC dedicated for recording and stimulation of neural network activity. Chip is designed in submicron CMOS 180nm technology, occupies 5×5 mm
²
of silicon area, and consumes only 25 μW/channel. The low cut-off frequency can be tuned in the range 60 mHz-100 Hz while the mean high cut-off frequency is 4.7 kHz or 12 kHz. The recording channel voltage gain may be also changed. Mean measurement values show it may be either 139 V/V or 1100 V/V. The measured input referenced noise is 3.7 μV rms in band 100 Hz-12 kHz and 7.6 μV rms in band 3 Hz-12 kHz. For the input signals amplitude 1.5 mV, the THD is 1%. In order to satisfy requirements concerning spread of the main parameters of the multichannel system, each channel is equipped with the two corrections DAC's. These allow to obtain voltage gain equal to 139 V/V with the standard deviation std = 0.67 V/V, and low cut-off frequency equal to 60 mHz with the std = 30 mHz only. Each channel is equipped additionally with a stimulation circuits allowing to generate stimulation pulses in the 125 nA-512 μA current range with 8-bit resolution. All ASIC configurations are set thanks to on-chip digital register controlled by the on-chip LVDS receivers.