Lab-on-a-chip sensor for point-of-care measurement of manganese exposure

This paper reports on the development of a lab-on-achip (LOC) sensor for rapid electrochemical point-of-care (POC) measurement of biological exposure to manganese (Mn). The sensor was fabricated using an electrodeposited bismuth film as a working electrode, and Ag/AgCl reference and Au auxiliary electrodes. Measurement of Mn was demonstrated in the 0.9 nM - 9 muM range in blood using square wave stripping voltammetry (SWSV). The sensitivity was approximately 0.5 muA/nM.