Time-of-flight laser spectroscopy in biomedical diagnostics

Optical spectroscopy is becoming a very valuable diagnostic tool in biomedical research. Time-of-flight spectroscopy is a tool providing information regarding scattering and absorption properties of the tissue. A unique broadband time-resolved spectroscopy system for turbid media, consists of a mode-locked Ti:sapphire laser pumping a photonic crystal fibre (PCF) and a streak-camera in syncroscan mode. This system is based on the technique called time-correlated single photon counting (TCSPC). This equipment is designed to allow in vivo measurement of tissue optical properties of small tissue volumes.