Selective ablation of angiogenic blood vessels based on ultrafast laser microsurgery

We have developed a novel technique for selective surgery of angiogenic blood vessels based on ultrafast laser. Using a transgenic zebrafish
<Tg(flil:EGFP)y1>
embryos at a different developmental stage including 14-somite, 20-somite stage and 16-prim stage, we have demonstrated that the current method is very effective for a selective surgery of the vasculature structure in early developed stage.