Controlled Bio-Carriers Based on Magnetotactic Bacteria

Magnetotactic bacteria (MTB) can be controlled by an externally applied magnetic field. Their fast migration speed and quick response time, along with their capability to achieve 4 pN thrust force, make them well suited for micro-bio-actuators and bio-carriers. Here, we use conventional methods of microlithographyto construct a microfluidic device to evaluate the activity of MTB in microchannels. Experiments also prove that a single MC-1 MTB can push a 2μm bead in a well controlled manner. Finally, we discuss the advantages of MTB based bio-carriers and prospect for future applications.