Systems biology: an information-theoretic-based thermo-statistical approach

Recently we published a paper studying biological systems (system-level understanding in biological science), from the physical-chemical point of view, and involving irreversible thermodynamics and nonlinear kinetic theory of open systems which are founded on nonequilibrium statistical mechanics [1]. The reason of this research was to progress in direction of the knowledge of complex molecules, in particular biological systems, making use of the collective quantum model established by Frohlich to explain the electret phenomenon. Here is important to remember that Bernhard Gross and Herbert Frohlich maintained friendly relations across their careers. Here we present a resume of this paper, in which we considered the case of a very peculiar complex behavior in open boson systems sufficiently away, from equilibrium, which appear to have large relevance in the functioning of biological systems. This is, on the one hand, the so-called Frohlich leading in steady-state conditions to the emergence of a particular case of quantum-large-scale coherent ordering, of the type of a selforganizing-synergetic dissipative structure. Moreover, additional complexity emerges in the form of propagation, in this condensate, of signals (information) consisting of nearly undamped and undistorted, long-distance propagating, solitary waves (the pseudoparticle soliton). It can be accompanied by a so-called Frohlich-Cherenkov cone of emission of polar vibrations, and it is also possible the formation of "metastable states" of the form of the so-called bioelectrets. These are phenomena apparently working in biological processes, which are presently gaining relevant status on the basis of eventually providing a large-scale quantum-coherent behavior in cytoskeletons of neurons and the conscious (non-computational) activity in the brain.