Safety Evaluation of Polylactic Aid Cgarette

The safety of cigarette filter rods directly affects the safety of cigarette. In this paper, the safety of polylactic acid (PLA) tow as filter rod in cigarette safety was evaluated by the micronucleus rate of animal cells, the mutation test of Salmonella typhimurium in cigarette smoke condensate (CSC) and the acute toxicity test of cigarette smoke condensate (CSC). The results showed that, the acute toxicity and micronucleus increase of animals were not observed under the test dose of PLA tow and PLA glue, and there was no obvious mutagenicity of PLA tow and PLA glue to Salmonella typhimurium. Moreover, there was no significant difference in the cytotoxicity, mutagenicity and micronucleus of Salmonella typhimurium between the conventional and PLA filter rod cigarettes.