Simulatenous glucose sensing and powering of glucometer

Although recent research has theoretically demonstrated that enzymatic glucose biofuel cell can be used to power a contact lens-based glucose sensor, such a practical system does not exist. Here, we developed a novel closed loop system consisting of a charge pump circuit and a step up DC converter circuit that is powered by a single enzymatic glucose biofuel cell at physiological conditions. This system is capable of simultaneously sensing glucose with a sensitivity of 86.42 Hz/cm
²
.M and producing a steady 3.25 V
_dc
output supply to drive low power devices such as commercially available glucometer. Moreover, this system relies on a novel glucose sensing technique which involves the monitoring of the charge/discharge frequency of the transducer capacitor as opposed to the invasive technique currently employed by commercially available glucose monitoring systems that require the implementation of battery-operated potentiostat.